Nasir Ali Afsar



  • MBBS, Liaquat Medical College, University of Sindh, Pakistan, Year 1997.
  • MPhil (Pharmacology), Ziauddin University, Karachi, Year 2005.
  • PhD (Pharmacology), Ziauddin University, Karachi. In collaboration with University of Kiel, Germany, Year 2011.
  • MERC (Medical Education Research Cert.), Association of American Medical Colleges, USA, Year 2012.
  • Simulation Instructor Program, (Simulation) Center for Advanced Pediatric and Perinatal Education, Stanford University, USA, Year 2017.


  • Professor of Pharmacology, 2018-to date, Jinnah Medical and Dental College, Karachi, Pakistan.
  • Associate Professor of Pharmacology, 2012-2018, Jinnah Medical and Dental College, Karachi, Pakistan.
  • Associate Professor of Pharmacology, 2010, Ziauddin University and Jinnah Medical and Dental College, Karachi, Pakistan.
  • Senior Lecturer (Research), 2011-2018, Alfaisal University, Riyadh, Saudi Arabia.
  • Assistant Professor of Pharmacology, 2005-2010, Ziauddin University, Karachi, Pakistan.
  • Instructor/Lecturer of Pharmacology, 2001-2005, Ziauddin University, Karachi, Pakistan.
  • Demonstrator/Lecturer of Pharmacology, 1999-2000, Isra University, Hyderabad, Pakistan.
  • Clinical Internship/House Job: 1998-1999, Internal Medicine, Pediatrics, and General Surgery at Liaquat Medical College Hospital Hyderabad/ Jamshoro, Pakistan.
  • Other:
  • Visiting Faculty, April 2013, Department of Pharmacology, Faculty of Medicine, Ataturk University, Erzurum, Turkey.
  • Member of International Outreach Committee of CSPT since July 2018

Research Focus

  • My research focuses basic and clinical pharmacology, pharmacogenetics and toxicology. Major research projects include, elucidation of genetic basis of pharmacokinetics and pharmacodynamics in cancer patients (such as breast cancer, acute myelogenous leukemia), genomic profiling of drug metabolizing enzymes and ABC transporters, role of aldehyde metabolism in atherosclerosis and coronary artery disease, environmental toxicogenomics, behavioral toxicology and other pharmacogenomic projects.
  • In addition, projects in clinical simulation, medical education, learning behavior modulation, and behavioral psychology are also currently active.


  • Pharmacology, Pharmacogenetics, Chemotherapy, Clinical Simulation, Medical Education.


  • 2019; Implications of genetic variation of common Drug Metabolizing Enzymes and ABC Transporters among Pakistani Population. Sci Rep. In press.
  • 2018; Lung resistance-related protein (LRP) predicts favorable therapeutic outcome in Acute Myeloid Leukemia. Sci Rep 9:378. doi: 10.1038/s41598-018-36780-8.
  • 2018; Gene Expression of hENT1, dCK, CDA, dCMPD, and Topoisomerase IIα as an indicator of chemotherapy response in AML treated with Cytarabine and Daunorubicin. Cancer Manag Res 10:5573-89. doi: 10.2147/CMAR.S181299.
  • 2018; Bax, Bcl-2 and Bax/Bcl-2 as Prognostic Markers in Acute Myeloid Leukemia. Are we ready for Bcl-2 directed therapy? Cancer Manag Res 10:403-16.
  • 2018; Evaluation of effectiveness of a Pediatric Simulation Course in Procedural Skills for Pediatric Residents – A Pilot Study. J Pak Med Assoc 68:240-6.
  • 2017; Objectivity in Subjectivity: Do Students’ Self and Peer Assessments Correlate with Examiners’ Subjective and Objective Assessment in Clinical Skills? A Prospective Study. BMJ Open 7(5):e012289. doi: 10.1136/bmjopen-2016-012289.
  • 2016; A Combined Approach of Clinical Skills Training Utilizing Near-Peers, In-Campus Faculty and Clinicians: An Innovative Integrated Model. Med Teach 38:S52-9.
  • 2015; Stress, anxiety, and depression among medical students in a multiethnic setting. Neuropsychiatr Dis Treat 11:1713-22.
  • 2012; Relationship of drug metabolizing enzyme genotype to plasma levels as well as myelotoxicity of cyclophosphamide in breast cancer patients. Eur J Clin Pharmacol 68:389-95.
  • 2010; Genotype Frequencies of selected Drug Metabolizing Enzymes and ABC Drug Transporters among Breast Cancer Patients on FAC Chemotherapy. Basic Clin Pharmacol Toxicol 107:570-6.
  • 2010; Breast Cancer Pattern and Chemotherapy Response – an Institutional Study in Pakistan. Asian Pac J Cancer Prev, 11:825-30.
  • 2008; Effect of low dose oral pill on hemostatic parameters in a set of Pakistani population. J Pak Med Assoc. 58: 229-33.
  • 2007; Homeopathy – Much Ado About Nothing. J Pak Med Assoc. 57: 275.
  • 2005; Effect of a ‘progestin only’ contraceptive on platelet aggregation in a Pakistani set of population. J Ayub Med Coll. 17:21-5.
  • 2004; Use of norethisterone oenanthate and predisposition to thrombosis. J Coll Physicians Surg Pak. 14:556-9. Reprint available on request.