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| Description | Name |
|---|---|
| The Chancellor, who will be its Chairman | Prof. Dr. Syed Tariq Sohail |
| The Vice Chancellor | Prof. Dr. Mohammed Saeed Qureishy |
| The Pro-Vice Chancellor | Mr. Syed Bulent Sohail Dr. Shahid Baqar SI (M) |
| A judge of High Court to be nominated by the Chief Justice of the High Court of Sindh | Honorable Mr. Justice Muhammad Faisal Kamal Alam |
| Two members of Provincial Assembly of Sindh to be nominated by the speaker | Mr. Muhammad Yousuf Baloch (MPA) Mr. Abdul Razaq Raja (MPA) |
| The Chairman, Sindh Higher Education Commission or his nominee | Prof. Dr. Tariq Rafi |
| The Chairman, Charter Inspection and Evaluation Committee or his nominee | Prof. Dr. Sarosh Hashmat Lodi |
| Two Deans to be appointed by the Chancellor in consultation with the Vice Chancellor | Prof. Dr. Rizwana S. Waraich Prof. Dr. Syed Jaffar Ahmed |
| The Secretary, Universities and Board or his nominee | Mr. Muhammad Abbas Baloch |
| One nominee of the Parton | Senator Mian Raza Rabbani |
| The President, Pakistan Medical & Dental Council or his nominee | Prof. Dr. Rizwan Taj |
| President Chamber of Commerce and Industries karachi or his representative | Mr. Rehan Hanif |
| One scientist of national and international repute to be nominated by the Board | Prof. Dr. Ambreen Usmani |
| Two trustees nominated by the Trust | Mrs. Ghazala Sohail Ms. Maham Sohail |
| Two persons of eminence representing various discipline and professions nominated by the Chancellor | Lt. Gr. (R) Mr. Moin Uddin Haider Prof. Dr. Fadieleh A. Sohail |
| The Director of Finance | Dr. Syed Adnan Tariq Sohail |
| The Director of Planning | Prof. Dr. Atif Mahmood |
| The Registrar who shall act as the Secretory of the Board | Dr. Sabeeh H. Jaffery |